MRSA tagged posts

Chemical Synthesis Breakthrough holds promise for Future Antibiotics

Graphical abstract: Total synthesis of micrococcin P1 and thiocillin I enabled by Mo(vi) catalyst

 Total synthesis of micrococcin P1 and thiocillin I enabled by Mo(vi) catalystChemical Science, 2019; DOI: 10.1039/C8SC04885A

University of Colorado Boulder chemistry researchers have developed a novel way to synthesize and optimize a naturally-occurring antibiotic compound that could one day be used to fight lethal drug-resistant infections such as Staphylococcus aureus, commonly known as MRSA.

Antibiotic-resistant infections afflict over 2 million people annually and result in over 23,000 deaths in the U.S. each year, according to the Centers for Disease Control and Prevention (CDC). A 2018 study by the CDC’s European counterpart found that drug-resistant superbugs were responsible for 33,000 deaths across Europe in 2015.

Researchers have previously identified thiopepti...

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Probiotic Bacillus Eliminates Staphylococcus bacteria – Additional studies of common supplement planned.

Exclusion of S. aureus colonization by dietary Bacillus in a human population.

Exclusion of S. aureus colonization by dietary Bacillus in a human population.

A new study from National Institutes of Health scientists and their Thai colleagues shows that a “good” bacterium commonly found in probiotic digestive supplements helps eliminate Staphylococcus aureus, a type of bacteria that can cause serious antibiotic-resistant infections. The researchers, led by scientists at NIH’s National Institute of Allergy and Infectious Diseases (NIAID), unexpectedly found that Bacillus bacteria prevented S. aureus bacteria from growing in the gut and nose of healthy individuals. Then, using a mouse study model, they identified exactly how that happens. Researchers from Mahidol University and Rajamangala University of Technology in Thailand collaborated on the project.

“Probiotics fre...

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An eNose is able to Sniff out Bacteria that cause Soft Tissue Infections

Image result for An eNose is able to sniff out bacteria that cause soft tissue infections

Electronic Nose in the Detection of Wound Infection Bacteria from Bacterial Cultures: A Proof-of-Principle Study

A recent study conducted at the University of Tampere, Tampere University of Technology, Pirkanmaa Hospital District and Fimlab in Finland has concluded that an electronic nose (eNose) can be used to identify the most common bacteria causing soft tissue infections. The eNose can be used to detect the bacteria without the prior preparation of samples, and the system was capable of differentiating methicillin-resistant Staphylococcus aureus (MRSA) from methicillin-sensitive Staphylococcus aureus (MSSA).

Skin and soft tissue infections are common diseases that need medical treatment...

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Anti-Bacterial Fabric Holds Promise for Fighting Superbug

antisuperbacteria mask

Proto-type anti-super-bacterial masks, made of antibacterial fabric.

A Korean industry-academic collaborative group has recently developed an anti-bacterial fabric that are effective against antibiotic-resistant superbugs ie Staphylococcus aureus strains. Antibiotics have proven to be a valuable weapon in the fight against infectious bacteria. But widespread use of antibiotics has resulted in antibiotic-resistant bacteria . Every year, 0.7 million patients die from a drug-resistant “superbug.” Moreover, nosocomial infections, ie hospital-acquired infections, have become a growing problem.

Consequently, as part of a local public health project, UNIST, Yeejoo Co., Ltd...

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