mtDNA variation tagged posts

Researchers find COVID-19 causes Mitochondrial Dysfunction in Heart and other Organs

Researchers find COVID-19 causes mitochondrial dysfunction in heart and other organs
A summary of prominent mRNA expression changes observed in COVID-19-derived nasopharyngeal samples collected early in infection when viral titers were high, SARS-CoV-2-positive rodent lungs when viral titers were in decline, and autopsy COVID-19 samples in which the virus had been cleared. Credit: Joseph W. Guarnieri, Gabrielle Widjaja, and Douglas C. Wallace.

Since the beginning of the COVID-19 pandemic caused by the SARS-CoV-2 virus, researchers have been trying to determine why this virus creates such negative long-term effects compared with most coronaviruses.

Now, a multi-institutional consortium of researchers led by a team at Children’s Hospital of Philadelphia (CHOP) and the COVID-19 International Research Team (COV-IRT) has found that the genes of the mitochondria can be ne...

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