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    muscle regeneration tagged posts

    Scientists reveal the Mechanism of Skeletal Muscle Stem Cell Activation in Muscle Regeneration

    February 25, 2022, Categories  Biology/Biotechnology, Health/Medical

    Discordant proteomic and transcriptomic signatures reveal a potential translational control mechanism during the SC quiescence-to-activation transition. a Schematic illustration of the workflow for the proteomic analysis of FACS-isolated SCs. The SCs were sorted from Pax7-nGFP mice. QSCs were sorted from 0.5% PFA-perfused mice. fiSCs were sorted from unperfused mice. Injured ASCs (iASCs) were sorted from 3 days 1.2% BaCl2 injured mice. Cultured ASCs (cASCs) were 2 days cultured SCs. (n = 2 independent experiments). b Hierarchical clustering of the protein expression (in the number of spectra) for QSCs, fiSCs, iASCs, and cASCs. c Heatmap of representative expression for cell cycle, quiescence, and activation-specific proteins of QSCs, fiSCs, iASCs, and cASCs...
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    Massage doesn’t just make Muscles feel better, it makes them Heal Faster and Stronger

    October 7, 2021, Categories  Biology/Biotechnology, Health/Medical

    Immunofluorescence images show that when an injured muscle is treated with mechanotherapy (right), its muscle fiber type composition changes compared to untreated muscles (left). The resulting composition of the treated muscle is more similar to that of healthy muscle, implying that treatment helps restore proper muscle function. Credit: Wyss Institute at Harvard University

    Study in mice confirms link between mechanotherapy and immunotherapy in muscle regeneration. Massage has been used to treat sore, injured muscles for more than 3,000 years, and today many athletes swear by massage guns to rehabilitate their bodies...

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    How to boost muscle regeneration and rebuild tissue

    May 27, 2021, Categories  Biology/Biotechnology, Health/Medical

    Induction of Yamanaka factors (OKSM) in muscle fibers increases the number of myogenic progenitors. Top, control; bottom, treatment. Red-pink color is Pax7, a muscle stem-cell marker. Blue indicates muscle nuclei.
    Credit: Salk Institute

    Clues about molecular changes underlying muscle loss tied to aging. In work that could one day help athletes as well as aging adults regenerate tissue more effectively, scientists increased the regeneration of muscle cells in mice by activating the precursors of muscle cells.

    One of the many effects of aging is loss of muscle mass, which contributes to disability in older people...

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