NAD+ pathway tagged posts

Pathway Linked to Slower Aging also Fuels Brain Cancer

Pathway linked to slower aging also fuels brain cancer

Researchers have shown that a metabolic pathway associated with slowing aging also drives brain cancer. In the image above, cancer stem cells in a mouse brain section glow fluorescent green, allowing researchers to study the effect of inhibiting the pathway on the ability of cancer stem cells to survive and proliferate. Credit: AMIT GUJAR AND ALBERT H. KIM

While a particular metabolic pathway shows potential to slow down the aging process, new research indicates a downside: That same pathway may drive brain cancer. The pathway, known as the nicotinamide adenine dinucleotide (NAD+) pathway, is overactive in a most deadly form of brain cancer, glioblastoma, according to a study by researchers at Washington University School of Medicine in St. Louis...

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