Ranallo, S. et al. “Antibody powered nucleic acid release using a DNA-based nanomachine.” Nature Communications, April 2017. doi: 10.1038/ncomms15150 (2017)
An international team from the University of Rome Tor Vergata and the University of Montreal has reported, in a paper published this week in Nature Communications, the design and synthesis of a nanoscale molecular slingshot made of DNA that is 20,000 times smaller than a human hair. This molecular slingshot could “shoot” and deliver drugs at precise locations in the human body once triggered by specific disease markers.
The molecular slingshot is only a few nanometres long and is composed of a synthetic DNA strand that can load a drug and then effectively act as the rubber band of the slingshot...
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