nanotechnology tagged posts

Scientists use Nanotechnology to Detect Bone-Healing Stem Cells

Microscopic image of enriched skeletal stem cells using gold nanoparticles.

Researchers at the University of Southampton have developed a new way of using nanomaterials to identify and enrich skeletal stem cells — a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost or damaged bone.

Working together, a team of physicists, chemists and tissue engineering experts used specially designed gold nanoparticles to ‘seek out’ specific human bone stem cells — creating a fluorescent glow to reveal their presence among other types of cells and allow them to be isolated or ‘enriched’.

The researchers concluded their new technique is simpler and quicker than other methods and up to 50-500 times more effective at enriching stem cells.

The ...

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Nanotechnology: Nanoparticles as weapons against Cancer

The amorphous nanoparticles dissolve very efficiently in the cell. Source: von Schirnding et al., Chem 2020
The amorphous nanoparticles dissolve very efficiently in the cell. Source: von Schirnding et al., Chem 2020

Researchers have developed a novel type of nanoparticle that efficiently and selectively kills cancer cells, thus opening up new therapeutic options for the treatment of tumors. Many chemotherapeutic agents used to treat cancers are associated with side-effects of varying severity, because they are toxic to normal cells as well as malignant tumors. This has motivated the search for effective alternatives to the synthetic pharmaceuticals with which most cancers are currently treated...

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Researchers use Nanotechnology to develop new Treatment for Endometriosis

Credit: CC0 Public Domain

Scientists have developed a precise, nanotechnology-based treatment to alleviate the pain and fertility problems associated with endometriosis, a common gynecological condition in women of childbearing age.

Research led by Oleh Taratula of the Oregon State University College of Pharmacy and Ov Slayden of the Oregon National Primate Research Center at Oregon Health & Science University used photo-responsive nanoparticles loaded with dye to find and remove the lesions associated with the disorder.

The endometrium is the innermost layer of the uterus, and endometriosis occurs when endometrium-like tissue forms lesions outside of the uterine cavity—usually involving the ovaries, the fallopian tubes and the tissue lining the pelvis.

On rare occasions, en...

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Minute Levels of Disease detected with Nanotechnology-enhanced Biochip


a Schematic representation at various stages of biosensor fabrication: (i) Bare electrodes (ii) SAM layer on the bare electrodes (iii) immobilized gold nano particles on the SAM layer (iv) Antibody immobilization on the electrodes (v) antigen–antibody conjugation on the electrodes. b Real image of the biosensor with microchannel

The difficulty in spotting minute amounts of disease circulating in the bloodstream has proven a stumbling block in the detection and treatment of cancers that advance stealthily with few symptoms. With a novel electrochemical biosensing device that identifies the tiniest signals these biomarkers emit, a pair of NJIT inventors are hoping to bridge this gap.

Their work in disease detection is an illustration of the power of electrical sensing – and the gr...

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