nasal spray tagged posts

A clinical trial led by Weill Cornell Medicine investigators showed that a nasal spray that patients administer at home, without a physician, successfully and safely treated recurrent episodes of a condition that causes rapid abnormal heart rhythms. The study, published March 25 in the Journal of the American College of Cardiology, provides real-world evidence that a wide range of patients can safely and effectively use the experimental drug, called etripamil, to treat recurrent paroxysmal supraventricular tachycardia (PSVT) episodes at home, potentially sparing them the need for repeated hospital trips for more invasive treatments.

The study is the latest in a series of studies by lead author Dr...

Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer’s Aβ peptide

New Alzheimer’s Rx could be delivered as nasal spray. A novel treatment could block the development of Alzheimer’s disease using microscopic droplets of fat, nanoliposomes, coated in protein fragments to carry drugs into the brain. This treatment approach, which is used to target drugs to cancer cells, has been successfully applied to Alzheimer’s disease for the first time, restoring memory loss in mice. The method stops amyloid protein accumulating into plaques, even at low concentrations.

Mice that were genetically altered to develop Alzheimer’s disease were injected with the nanoliposomes for three weeks...