This is a fluorescent microscopy image showing accumulation of phosphatidylethanolamine (PE, red) in human dendritic cells treated with synthetic F. tularensis PE containing liposomes. Blue indicates the cell nucleus.
Credit: NIAID
NIH scientists see therapeutic potential against bacteria, viruses. National Institutes of Health researchers have identified a naturally occurring lipid – a waxy, fatty acid – used by a disease-causing bacterium to impair the host immune response and increase the chance of infection. Inadvertently, they also may have found a potent inflammation therapy against bacterial and viral diseases.
Lipids are known to help Francisella tularensis bacteria, the cause of tularemia, to suppress host inflammation when infecting mouse and human cells...
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