NaV1.7 tagged posts

Compound provides innovative Pain Relief

Compound 194 (left) was developed by researchers to uncouple the interaction between CRMP2 and the enzyme Ubc9, which indirectly regulates the sodium ion channel NaV1.7. A new study showed that the resulting reduction in sodium currents reduced pain. (Image: Samantha Perez-Miller, Aude Chefdeville and Rajesh Khanna)

Researchers targeted a common sodium ion channel to reverse pain, with positive results that could lead to a non-addictive solution to treat pain. Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

Most people experience pain at some point in their lives, and the...

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