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‘Young’ immune cells reverse signs of neurodegenerative brain changes in preclinical study

Cedars-Sinai investigators used “young” immune cells created from stem cells to reverse signs of aging in the brain. Image by Getty.

“Young” immune cells created by Cedars-Sinai investigators reversed signs of aging and Alzheimer’s disease in the brains of laboratory mice, according to a study published in the journal Advanced Science.

The immune cells, which were produced from human stem cells, could be used to develop new treatments for neurological conditions in humans.

“Previous studies have shown that transfusions of blood or plasma from young mice improved cognitive decline in older mice, but that is difficult to translate into a therapy,” said Clive Svendsen, Ph.D...

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