Neuroglobin expression in the human brain, from the Allen Human Brain Atlas. Credit: brain-map.org
A team at the MRC Clinical Sciences Centre (CSC), Imperial College London, has found an important part of the machinery that switches on a gene known to protect against Alzheimer’s Disease. Working in collaboration with scientists at the Hong Kong University (HKU) and the Erasmus University in Rotterdam, CSC associate professor Richard Festenstein explored the steps by which this Neuroglobin gene is gradually switched on, or up-regulated. Neuroglobin has previously been shown to protect against Alzheimer’s disease in mice in which it makes the protective Neuroglobin...
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