mRNA expression analysis of EWAS-related genes in AD CA1 pyramidal neurons AD CA1 astrocytes and AD CA1 microglia. Only two of the seven identified transcripts in the EWAS study were significantly differentially expressed, BIN1 in AD neurons and SERPINF2 in AD microglia. * indicates p < .05.
ANK1 gene expression change found in brain’s microglia cells associated with neuroinflammation. Researchers led by Arizona State University (ASU) and the Translational Genomics Research Institute (TGen) have identified altered expression of a gene called ANK1, which only recently has been associated with memory robbing Alzheimer’s disease, in specific cells in the brain...
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