next generation sequencing tagged posts

Blood Test Detects over 50 Types of Cancer, some before symptoms appear

Identification of cancer status for more than 50 cancer types, as well as tissue of origin localization, from a single blood draw. Cell-free DNA is isolated from blood samples drawn from a patient without cancer (top) or with cancer (bottom), and subjected to a targeted methylation sequencing assay. Sequencing results identifying methylated (red) or unmethylated (blue) CpG regions are fed into a machine-learning classifier that can identify the presence or absence of cancer, as well as identify the tissue of origin (TOO).

In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within the body with a high degree of accuracy, according to an international team of researchers led by Dana-Farber Cancer Institute and...

Read More

Genetic Sequencing could influence Treatment for nearly 3/4 of Advanced Cancer patients

Nearly three-quarters of patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor’s genetic landscape, a new analysis finds.

Nearly three-quarters of patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor’s genetic landscape, a new analysis finds.

More biomarker-based clinical trials will increase opportunities. A new analysis finds that nearly 3/4 of 500 patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor’s genetic landscape. The study suggests the value of next generation sequencing, a sophisticated method of evaluating the DNA and RNA of a tumor to help direct treatment.

A report on the first 500 patients with advanced solid tumors to go through the University of Michigan Comprehensive Cancer Center’s sequencing program found...

Read More