VitB3 3D model
It will allow for novel drug development for obesity, diabetes type II and related metabolic diseases. A small molecule N1-methylnicotinamide prevents metabolic complications caused by a high-fat diet.
“Our laboratory investigates the metabolic effects of nicotinamide adenine dinucleotide [NAD+], a metabolite derived from a form of vitamin B3 called nicotinamide,” explained assistant Prof Pavlos Pissios. NAD+ is central to intermediary metabolism, the intracellular process by which food is converted into cellular components in the body.
“Like reservatrol, which is found in red wine, NAD+ boosts the effects of the protein sirtuin 1 [Sirt1], which is known to provide many health benefits,” said Pissios...
Read More
Recent Comments