NKG2A+ tagged posts

Common Immune Response is found to be Protective Across Many Diseases

Common immune response protective across many diseases
Overview of study design, analytic methods, and dataset multi-omics. (A) Cartoon describing the collected single-cell and bulk multi-omic datasets with paired clinical data from infection, autoimmunity, and cancer contexts. (B) Cartoon depicting experimental and analytic strategies for single-cell and bulk data with a focus on NKG2A/C-expressing cell types. (C) Cartoon demonstrating NKG2A+ and NKG2C+ bias assignment at single-cell and bulk levels. (D) Cartoon displaying the different clinical and biological -omics to be compared between NKG2A+ and patients with an NKG2C+ bias. Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.113872

Combined, infection, autoimmunity and cancer account for 4 out of every 10 deaths worldwide, and represent major global health challenges...

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