NO tagged posts

Large study finds that Air Pollution Speeds Bone Loss from Osteoporosis

Air Pollution Speeds Bone Loss from Osteoporosis: Large Study
Bayesian kernel machine regression univariate exposure-response plots with 95% credible intervals for the effect of each pollutant on the different bone mineral density sites evaluated. Credit: eClinicalMedicine (2023). DOI: 10.1016/j.eclinm.2023.101864

Elevated levels of air pollutants are associated with bone damage among postmenopausal women, according to new research led by scientists at Columbia University Mailman School of Public Health. The effects were most evident on the lumbar spine, with nitrous oxides twice as damaging to the area as in normal aging.

The research findings appear in the journal eClinicalMedicine.

Previous studies on individual pollutants have suggested adverse effects on bone mineral density, osteoporosis risk, and fractures in older individuals...

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New Role for Immune Cells in Preventing Diabetes and Hypertension

 Eosinophils stimulate β3 adrenoreceptors through the release of soluble factors.

Eosinophils stimulate β3 adrenoreceptors through the release of soluble factors.

Immune cells which are reduced in number by obesity could be a new target to treat diseases such as type 2 diabetes and hypertension that affect overweight people, according to a collaborative study between The University of Manchester, Lund University and the University of Salford. In a study published in the journal Scientific Reports, reseachers investigated eosinophils. Eosinophils are present in perivascular adipose tissue (PVAT), which surrounds blood vessels and helps to maintain normal blood vessel function by reducing artery contraction.

The current research found that eosinophils were considerably reduced in the PVAT in obesity in mice, and that the PVAT function was severely impaired, contributing ...

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