Highlights •A triple-target CRISPR method achieved almost perfect knockout efficiency •SSS achieved non-invasive fully automated high-performance sleep phenotyping •Genetics without crossing revealed Nr3a as a short-sleeper gene
You may have wondered why some people seem to need less sleep. A number of so called short-sleeper genes, which are associated with little need for sleep, have recently been identified. RIKEN Quantitative Biology Center (QBiC) researchers have advanced sleep genetics research by developing a new method for monitoring mouse sleep cycles. The Snappy Sleep Stager is a non-invasive, automated sleep cycle monitoring system based on mouse respiration, or breathing...
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