NSAIDs tagged posts

Marked differences between males and females. The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis. The study in laboratory mice also shows marked differences between males and females.

Ibuprofen belongs to a group of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs, widely used over the counter to treat pain and fever...

Preventive strategies, targeting diet, drugs, body chemistry, mental health, pre-existing disease, and lifestyle may help to stave off dementia. This could be particularly important, given that, as yet, there is no cure, they say. The researchers wanted to look at the factors associated with the development of Alzheimer’s disease in a bid to determine the degree to which these might be modified and so potentially reduce overall risk.

They trawled key research databases, looking for relevant studies published in English from 1968 up to July 2014. Out of almost 17,000 studies, 323, covering 93 different potential risk factors and more than 5000 people, were suitable for inclusion in the analysis...