NSCLC tagged posts

Right Program could turn Immune Cells into Cancer Killers

A tumor-specific T cell engages with a tumor cell. Bystander T cells do not engage with the tumor. Credit: PNAS Dec. 10, 2002, Copyright (2002) National Academy of Sciences, U.S.A.

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different “program” that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

The findings, published in the August 5 issue of Nature, could lead to new ways to overcome tumor resistance to these treatments.

“Cancer immunotherapies have tremendous promise, but this promise only comes to fr...

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Panel of 5 serum microRNAs could lead to accurate, early diagnosis of NSCLC in ethnically diverse patients

 

Panel of 5 serum microRNAs could lead to accurate, early diagnosis of NSCLC in ethnically diverse patients

Early-stage Non-small-cell Lung Cancer is asymptomatic and difficult to detect since no blood test for NSCLC is currently available. In a new study, researchers identified a panel of five serum microRNAs as the potential biomarker for NSCLC diagnosis.

MiRNAs are a family of small, single-stranded non-coding RNAs that are critical regulators of numerous diseases, and their expression patterns have the potential to diagnose various types of cancer. This is the first multiethnic, multicentric, single-blind global analysis of miRNA expression patterns of NSCLC patients in four independent cohorts from five centers in both China and America...

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