OFC tagged posts

Glass half full or half empty? What you see may depend in part on the size of your orbitofrontal cortex. Optimistic people also tend to be less anxious, research finds. Credit: Graphic by Julie McMahon

A new study finds healthy adults who have larger OFCs tend to be more optimistic and less anxious. Anxiety disorders afflict roughly 44 million people in the U.S. These disorders disrupt lives and cost an estimated $42-$47 billion annually.

The orbitofrontal cortex, a brain region located just behind the eyes, is known to play a role in anxiety. The OFC integrates intellectual and emotional information and is essential to behavioral regulation. Previous studies have found links between the size of a person’s OFC and his or her susceptibility to anxiety...