oligodendrocyte precursor cells tagged posts

It is thus possible to encourage regeneration of the myelin sheath by inhibiting the action of PTPRZ in endogenous oligodendrocyte precursor cells, indicating a new potential treatment for demyelinating diseases. Normally, myelin is repaired, even if damaged, but the mechanism that controls remyelination was not well understood. In addition, in demyelinating diseases eg multiple sclerosis, the myelin sheath does not recover from damage and gets worse, finally leading to symptoms such as vision loss, limb numbness, and movement disorders. The research group of Professor Masaharu Noda and colleagues of the National Institute for Basic Biology, performed a detailed examination of the remyelinating process of damaged myelin using disease model mice...