oral microbiome tagged posts

A simple oral rinse could provide early detection of gastric cancer, the fourth-leading cause of cancer deaths worldwide, according to a study scheduled for presentation at Digestive Disease Week (DDW) 2024.

“In the cancer world, if you find patients after they’ve developed cancer, it’s a little too late,” said Shruthi Reddy Perati, MD, author and general surgery resident at Rutgers Robert Wood Johnson School of Medicine. “The ideal time to try to prevent cancer is when it’s just about to turn into cancer. We were able to identify people who had precancerous conditions. As a screening and prevention tool, this has enormous potential.”

Researchers analyzed bacteria samples from the mouths of 98 patients scheduled for endoscopy, including 30 known...

The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new University at Buffalo-led study.

The research sought to understand how P. gingivalis colonizes the mouth. The pathogen is unable to produce its own growth molecules until it achieves a large population in the oral microbiome (the community of microorganisms that live on and inside the body).

The answer: It borrows growth molecules from V...