organ-on-a-chip tagged posts

New Organ-on-a-Chip finds crucial interaction between Blood, Ovarian Cancer Tumors

Abhishek Jain and his team at Texas A&M are collaborating with researchers at MD Anderson Cancer Center and Rice University to develop and test their new microdevice, the ovarian tumor microenvironment-chip.
Texas A&M Engineering

In the evolving field of cancer biology and treatment, innovations in organ-on-a-chip microdevices allow researchers to discover more about the disease outside the human body. These organs-on-chips serve as a model of the state an actual cancer patient is in, thus allowing an opportunity to finding the correct treatment before administering it to the patient. At Texas A&M University, researchers are pushing these devices to new levels that could change the way clinicians approach cancer treatment, particularly ovarian cancer.

The team has recently submitted ...

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‘Gut-on-a-Chip’ system shows Intestinal Barrier Disruption is the onset initiator of Gut Inflammation

Biomedical engineering assistant professor Hyun Jung Kim with the gut-on-a-chip. Cockrell School of Engineering, The University of Texas at Austin

Biomedical engineering assistant professor Hyun Jung Kim with the gut-on-a-chip. Cockrell School of Engineering, The University of Texas at Austin

Once the gut barrier has been damaged, probiotics can be harmful just like any other bacteria. The first study investigating the mechanism of how a disease develops using human organ-on-a-chip technology has been successfully completed by engineers at The University of Texas at Austin.

Researchers from the Cockrell School of Engineering were able to shed light on a part of the human body – the digestive system – where many questions remain unanswered. Using their “gut inflammation-on-a-chip” microphysiological system, the research team confirmed that intestinal barrier disruption is the onset initiator of gut inflammation.

The study also include...

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