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    ovarian cancer tagged posts

    New Technology can Detect Tiny Ovarian Tumors

    April 10, 2017, Categories  Biology/Biotechnology, Health/Medical

    A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. Image: Nephron/CC BY-SA 3.0

    A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. A high-magnification micrograph of an ovarian clear cell carcinoma. The images show, focally, the characteristic clear cells with prominent nucleoli and the typical hyaline globules. Image: Nephron/CC BY-SA 3.0

    ‘Synthetic biomarkers’ could be used to diagnose ovarian cancer months earlier than now possible. Most ovarian cancer is diagnosed at such late stages that patients’ survival rates are poor. However, if the cancer is detected earlier, 5-year survival rates can be greater than 90%...

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    New Gene Identified as Cause, Early Indicator of Breast Cancer

    March 19, 2016, Categories  Biology/Biotechnology, Health/Medical

    Dr. Nahid Mivechi, cell biologist and radiobiologist, a group leader at the Cancer Center and a study co-author; Dr. Nita Maihle, MCG cancer biologist, associate center director for education at the university's Cancer Center and a study co-author; Dr. Lan Ko, cancer biologist in the Department of Pathology at the Medical College of Georgia at Augusta University and at the Georgia Cancer Center at AU Credit: Phil Jones

    Dr. Nahid Mivechi, cell biologist and radiobiologist, a group leader at the Cancer Center and a study co-author; Dr. Nita Maihle, MCG cancer biologist, associate center director for education at the university’s Cancer Center and a study co-author; Dr. Lan Ko, cancer biologist in the Department of Pathology at the Medical College of Georgia at Augusta University and at the Georgia Cancer Center at AU Credit: Phil Jones

    When mutated, a gene known for its ability to repair DNA, appears to instead cause breast cancer. The gene GT198, whether mutated by genetics and/or environmental factors, has strong potential as both as a way to diagnose breast cancer early and as a new treatment target, said Dr. Lan Ko...

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    Study Uncovers inherited Genetic Susceptibility across 12 Cancer Types?

    December 22, 2015, Categories  Biology/Biotechnology, Health/Medical

    A new study sheds light on the inherited components of 12 cancer types. The research confirmed the well-known heritability of breast and ovarian cancers and found a surprising inherited component to stomach cancer. In the graphic above, Lung 1 is lung squamous cell carcinoma, and Lung 2 is lung adenocarcinoma. Credit: Sara Dickherber

    A new study sheds light on the inherited components of 12 cancer types. The research confirmed the well-known heritability of breast and ovarian cancers and found a surprising inherited component to stomach cancer. In the graphic above, Lung 1 is lung squamous cell carcinoma, and Lung 2 is lung adenocarcinoma. Credit: Sara Dickherber

    In a new analysis, researchers have shed light on these hereditary elements across 12 cancer types – showing a surprising inherited component to stomach cancer and providing some needed clarity on the consequences of certain types of mutations in well-known breast cancer susceptibility genes, BRCA1 and BRCA2...

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    USP15 protein has been Identified as Novel Target for therapy against Cancer Progression

    December 21, 2015, Categories  Biology/Biotechnology, Health/Medical

    Molecular model showing the novel proposed mechanism for the activation of SMURF2. The C-lobe (in yellow) of the SMURF2 protein interacts with an ubiquitin molecule (in green), which was transferred to SMURF2 by USP15. Credit: Image courtesy of National University of Singapore

    Molecular model showing the novel proposed mechanism for the activation of SMURF2. The C-lobe (in yellow) of the SMURF2 protein interacts with an ubiquitin molecule (in green), which was transferred to SMURF2 by USP15. Credit: Image courtesy of National University of Singapore

    In certain settings, the TGF-beta pathway can act as an oncogene, enhancing cancer progression in humans. The activation of this pathway can increase the growth of tumors by promoting cell invasion, activating cancer stem cells, and in some cases, promoting the spread of cancer. In recent years, a number of deubiquitinating enzymes have been shown to regulate the TGF-β pathway and may potentially be considered as a new class of drug targets...

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