paglioclase tagged posts

Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study published in Nature Communications found that phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.

PAG was shown to interact with beta-2 adrenergic receptors to influence how forcefully the heart muscle cells contract—a process that investigators believe contributes to he...

Moon crust formation graphic. Credit: The University of Texas at Austin/Jackson School of Geosciences

A team led by The University of Texas at Austin Jackson School of Geosciences took to the lab to recreate the magmatic melt that once formed the lunar surface and uncovered new insights on how the modern moonscape came to be. Their study shows that the Moon’s crust initially formed from rock floating to the surface of the magma ocean and cooling. However, the team also found that one of the great mysteries of the lunar body’s formation – how it could develop a crust composed of just one mineral – cannot be explained by the initial crust formation and must have been the result of some secondary event.

“It’s fascinating to me that there could be a body as big as the Moon that was completely ...