pain relief tagged posts

Compound provides innovative Pain Relief

Compound 194 (left) was developed by researchers to uncouple the interaction between CRMP2 and the enzyme Ubc9, which indirectly regulates the sodium ion channel NaV1.7. A new study showed that the resulting reduction in sodium currents reduced pain. (Image: Samantha Perez-Miller, Aude Chefdeville and Rajesh Khanna)

Researchers targeted a common sodium ion channel to reverse pain, with positive results that could lead to a non-addictive solution to treat pain. Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

Most people experience pain at some point in their lives, and the...

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Placebo Sweet Spot for Pain Relief identified in Brain

The yellow and red sections of this brain image shows the unique brain region — the mid frontal gyrus — which Northwestern scientists discovered is responsible for placebo response in pain relief. Credit: Marwan Baliki

The yellow and red sections of this brain image shows the unique brain region — the mid frontal gyrus — which Northwestern scientists discovered is responsible for placebo response in pain relief. Credit: Marwan Baliki

Scientists have identified for the first time the region in the brain responsible for the “placebo effect” in pain relief, when a fake treatment actually results in substantial reduction of pain, according to new research from Northwestern Medicine and the Rehabilitation Institute of Chicago (RIC).

Pinpointing the sweet spot of the pain killing placebo effect could result in the design of more personalized medicine for the 100 million Americans with chronic pain...

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1st ever Ibuprofen Patch Produced and Patented:

Medherant Patch. Credit: Image courtesy of University of Warwick

Medherant Patch. Credit: Image courtesy of University of Warwick

It delivers drug directly via skin to where needed at a consistent dose rate. Researchers at the University of Warwick have worked with Coventry-based Medherant, a Warwick spinout company in developing a transparent adhesive patch that can consistently deliver a prolonged high dose of the painkiller ibuprofen directly through the skin. The University of Warwick researchers and Medherant have found a way to incoporate significant amounts of the drug (up to 30% weight) into the polymer matrix that sticks the patch to the patient’s skin with the drug then being delivered at a steady rate over up to 12 hours...

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