Treating postoperative and chronic inflammatory pain should now be possible without causing side effects. Doing so would substantially improve patient quality of life. (Stock image) Credit: © imacoconut / Fotolia
Researchers discover new mechanism of action. Researchers from Charité – Universitätsmedizin Berlin have discovered a new way of developing painkillers. The team of researchers used computational simulation to analyze interactions at opioid receptors. When used in an animal model, their prototype of a morphine-like molecule was able to produce substantial pain relief in inflamed tissues. However, healthy tissues remained unaffected, suggesting the severe side effects might be avoided.
“By analyzing drug-opioid receptor interactions in damaged tissues, as opposed to healthy tiss...
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