
This image shows an ordered string or ribbon of Toxoplasma parasites with their nuclei shown in blue and the parasite rhoptries that secrete the effectors shown in green. Credit: Barbara Fox and colleagues
Scientists identified the specific proteins secreted by the parasite Toxoplasma gondii that cause the immune system in mice to attack established ovarian tumors. A promising strategy in the fight against cancer is to use the body’s own immune system to remove tumor cells, but due to a phenomenon called immune tolerance, the immune system has a difficult time identifying which cells to attack. In the new study, scientists built upon previous discoveries that a safe, non-reproducing vaccine strain of T...
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