Enzyme with central role in cancer and type 2 diabetes also activates. Researchers have discovered a direct link between a master sensor of cell stress and a protein that protects the power stations of cells. The same pathway is also tied to type 2 diabetes and cancer, which could open a new avenue for treating all three diseases.
When cells are stressed, chemical alarms go off, setting in motion a flurry of activity that protects the cell’s most important players. During the rush, a protein called Parkin hurries to protect the mitochondria, the power stations that generate energy for the cell. Now Salk researchers have discovered a direct link between a master sensor of cell stress and Parkin itself...
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