Parkinson’s disease tagged posts

Research findings focus on people with a sleep disorder, but could have broader implications. For people with a certain sleep disorder, a simple blood test could help predict the development of dementia years before symptoms appear, a new study indicates.

Idiopathic REM sleep behaviour disorder (iRBD) causes people to physically act out their dreams while sleeping.

The disorder is also associated with a very high risk of Parkinson’s disease and a related condition called Dementia with Lewy Bodies.

This is a form of dementia that often causes memory and cognitive loss, as well as vivid visual hallucinations and movement difficulties similar to Parkinson’s.

McGill University researchers have discovered that a blood test, originally developed to detect Alzheimer’s disease, co...

A research team from the University of California, Irvine is the first to reveal that a molecule in the brain—ophthalmic acid—unexpectedly acts like a neurotransmitter similar to dopamine in regulating motor function, offering a new therapeutic target for Parkinson’s and other movement diseases.

In the study, published in the October issue of the journal Brain, researchers observed that ophthalmic acid binds to and activates calcium-sensing receptors in the brain, reversing the movement impairments of Parkinson’s mouse models for more than 20 hours.

The disabling neurogenerative disease affects millions of people worldwide over the age of 50...

High-intensity exercise induces brain-protective effects that have the potential to not just slow down but possibly reverse the neurodegeneration associated with Parkinson’s disease, a new pilot ...

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson’s disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

The variant, located in a mitochondrial microprotein dubbed SHLP2, was found to be highly protective against Parkinson’s disease; individuals with this mutation are half as likely to develop the disease as those who do not carry it. The variant form of the protein is relatively rare and is found primarily in people of European descent.

The findings appear in the journal Molecular Psychiatry.

First discovered by Pinchas Cohen at the USC Leonard Davis School in 2016, SHLP2 is made within the cell’s...