Parkinson’s disease tagged posts

Quantum Brain Sensors could be crucial in Spotting Dementia after scientists find they can Track Brain Waves

Lead research author Aikaterini Gialopsou with magnetic shield where participant brain signal measurements are taken

New highly sensitive quantum sensors for the brain may in the future be able to identify brain diseases such as dementia, ALS and Parkinson’s, by spotting a slowing in the speed at which signals travel across the brain. The research findings from a paper led by University of Sussex quantum physicists are published in Scientific Reports journal.

The quantum scanners being developed by the scientists can detect the magnetic fields generated when neurons fire. Measuring moment-to-moment changes in the brain, they track the speed at which signals move across the brain...

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Prostate Drug associated with Lower Risk of Parkinson’s disease

Parkinson's disease
Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia

Taking a particular type of medication to treat enlarged prostate is associated with a reduced risk of developing Parkinson’s disease, according to a large observational study led by researchers at the University of Iowa, with colleagues in Denmark and China.

The findings, published Feb. 1 in JAMA Neurology, provide compelling evidence that terazosin, and similar medications, might have the potential to prevent or delay the development of Parkinson’s disease.

The new study used data on almost 300,000 older men from two large, independent patient datasets — the Truven Health Analytics MarketScan database in the Uni...

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Tomatoes offer Affordable Source of Parkinson’s disease Drug

Metabolic engineering of tomato fruit enriched in L-DOPA
Author links open overlay panelDarioBreitelacPaulBrettaSalehAlseekhbAlisdair R.FerniebEugenioButelliaCathieMartina

Scientists have produced a tomato enriched in the Parkinson’s disease drug L-DOPA in what could become a new, affordable source of one of the world’s essential medicines.

The development of the genetically modified (GM) tomato has implications for developing nations where access to pharmaceutical drugs is restricted.

This novel use of tomato plants as a natural source of L-DOPA also offers benefits for people who suffer adverse effects — including nausea and behavioral complications — of chemically synthesised L-DOPA .

Tomato — was chosen as a widely cultivated crop that can be used for scaled up production a...

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One-time Treatment Generates New Neurons, Eliminates Parkinson’s disease in mice

Left: mouse astrocytes (green) before reprogramming; Right: neurons (red) induced from mouse astrocytes after reprogramming with PTB antisense oligonucleotide treatment.

Researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice’s Parkinson’s disease symptoms disappear.

Xiang-Dong Fu, PhD, has never been more excited about something in his entire career. He has long studied the basic biology of RNA, a genetic cousin of DNA, and the proteins that bind it. But a single discovery has launched Fu into a completely new field: neuroscience.

For decades, Fu and his team at University of California San Diego School of Medicine studied a pr...

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