‘The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling’ by Paolo Madeddu et al in Scientific Reports
A new discovery by University of Bristol scientists helps to explain how cells which surround blood vessels, pericytes, stimulate new blood vessels to grow with the hormone ‘leptin’ playing a key role. Leptin is produced by fat cells which helps to regulate energy balance in the body by inhibiting the appetite. This study, described in Scientific Reports, may have important implications for the treatment of heart attacks and also for cancer, the two main killers in the UK.
The growth of new blood vessels, ‘angiogenesis’, is an important process occurring both in health and disease...
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