Eosinophils stimulate β3 adrenoreceptors through the release of soluble factors.
Immune cells which are reduced in number by obesity could be a new target to treat diseases such as type 2 diabetes and hypertension that affect overweight people, according to a collaborative study between The University of Manchester, Lund University and the University of Salford. In a study published in the journal Scientific Reports, reseachers investigated eosinophils. Eosinophils are present in perivascular adipose tissue (PVAT), which surrounds blood vessels and helps to maintain normal blood vessel function by reducing artery contraction.
The current research found that eosinophils were considerably reduced in the PVAT in obesity in mice, and that the PVAT function was severely impaired, contributing ...
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