Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the most dangerous type of brain tumor. Study findings are published online in the journal Science Advances.
This enzyme plays a vital role in the hexosamine synthesis pathway, which is involved in the processes of protein and lipid glycosylation that allow tumors to rapidly grow. Lipid glycosylation is a process where sugar molecules attach to fats (lipids) in the body.
Researchers with The Ohio State University Comprehensive Cancer Center—Arthur G. James and Richard J. Solove Research Institute believe that targeting PGM3 can reduce tumor growth and eliminate glioblastoma cells.
“This research is important because it has found a new target called PGM3...
Read More
Recent Comments