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    Piezo1 tagged posts

    Study finds unleashing Treg cells may lead to Treatments for Multiple Sclerosis

    July 22, 2021, Categories  Biology/Biotechnology, Health/Medical

    Genetic deletion of Piezo1 in T cells leads to protection in autoimmunity: In the absence of Piezo1, Tregs expand more and, due to their increased numbers, are more effective in containing the damage inflicted by the effector T cells during an autoimmune neuroinflammation. Effector T cell function is not affected in the absence of Piezo1.
    CREDIT
    UCI School of Medicine

    In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

    Published this month in Science Advances, the new study illuminates the important role of Piezo1, a specialized p...

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