plaques tagged posts

Nanoparticle Chomps away Plaques that cause Heart Attacks

The dotted line outlines the atherosclerotic artery and the green represents our nanoparticles, which are in the plaque. The red indicates macrophages, which is the cell type that the nanoparticles are stimulating to eat the debris.

Michigan State University and Stanford University scientists have invented a nanoparticle that eats away – from the inside out – portions of plaques that cause heart attacks.

Bryan Smith, associate professor of biomedical engineering at MSU, and a team of scientists created a “Trojan Horse” nanoparticle that can be directed to eat debris, reducing and stabilizing plaque. The discovery could be a potential treatment for atherosclerosis, a leading cause of death in the United States.

The results, published in the current issue of Nature Nanotechno...

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Novel Nanoparticle-based approach Detects and Treats Oral Plaque Without Drugs

In this illustration, nanoparticles attach to or are taken up by the bacteria cells. Pan and his students are the first group to demonstrate that early detection of dental plaque in the clinic is possible using the regular intraoral X-ray machine which can seek out harmful bacteria populations. Credit: University of Illinois Laboratory for Materials in Medicine

In this illustration, nanoparticles attach to or are taken up by the bacteria cells. Pan and his students are the first group to demonstrate that early detection of dental plaque in the clinic is possible using the regular intraoral X-ray machine which can seek out harmful bacteria populations.
Credit: University of Illinois Laboratory for Materials in Medicine

When the good and bad bacteria in our mouth become imbalanced, the bad bacteria form a biofilm (aka plaque), which can cause cavities, and if left untreated over time, can lead to cardiovascular and other inflammatory diseases like diabetes and bacterial pneumonia.

A team of researchers from the University of Illinois has recently devised a practical nanotechnology-based method for detecting and treating the harmful bacteria that cau...

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Allergen in Red Meat linked to Heart Disease

Shown are cross-sectional ultrasound images of coronary arteries from patients enrolled in the study. Plaque buildup (colored areas) in an artery from a patient that lacks sensitivity to red meat allergen (left) is much lower than plaque levels in an artery from a patient with sensitivity to red meat allergen (right). Credit: Courtesy of Angela Taylor, M.D., University of Virginia Health System

Shown are cross-sectional ultrasound images of coronary arteries from patients enrolled in the study. Plaque buildup (colored areas) in an artery from a patient that lacks sensitivity to red meat allergen (left) is much lower than plaque levels in an artery from a patient with sensitivity to red meat allergen (right). Credit: Courtesy of Angela Taylor, M.D., University of Virginia Health System

A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart. While high saturated fat levels in red meat have long been known to contribute to heart disease for people in general, the new finding suggests that a subgroup of the population may be at heightened risk for a different reason – a food allergen...

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