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    Structure and Key Features of Critical Immune-surveilance Protein in Humans

    July 15, 2018, Categories  Biology/Biotechnology, Health/Medical

    Wen Zhou et al. Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance. Cell, 2018 DOI: 10.1016/j.cell.2018.06.026

    Wen Zhou et al. Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance. Cell, 2018 DOI: 10.1016/j.cell.2018.06.026

    Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections. The identification of two human-specific variations in the protein closes a critical knowledge gap in immunology and cancer biology.

    The human body is built for survival. Each one of its cells is closely guarded by a set of immune proteins armed with nearly foolproof radars that detect foreign or damaged DNA...

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