precursor to amylin — called Iselt amyloid peptide (Iapp) tagged posts

Metabolism Protein found to also regulate Feeding Behavior in the Brain

Scientists found evidence of the metabolism-regulating protein amylin, shown in red, present in multiple regions throughout a brain area called the hypothalamus. Experiments suggest amylin produced by hypothalamic neurons helps reduce food consumption together with leptin. Credit: Laboratory of Molecular Genetics at The Rockefeller University/Cell Metabolism

Scientists found evidence of the metabolism-regulating protein amylin, shown in red, present in multiple regions throughout a brain area called the hypothalamus. Experiments suggest amylin produced by hypothalamic neurons helps reduce food consumption together with leptin. Credit: Laboratory of Molecular Genetics at The Rockefeller University/Cell Metabolism

Feeling hungry or full leads us to change how much we eat, but the molecular wiring of this process is not well understood. Scientists have identified a new player in this circuit called amylin, which contributes to reducing food consumption in mice. Prof. Jeffrey Friedman said; “Amylin caught our attention when we were profiling a set of neurons in the hypothalamus, a part of the brain known to be involved in feeding behavior...

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