Spinster homolog 1 (Drosophila) SPNS1
In a new study, TSRI, Florida scientists have shown how 2 genes “balance” each other to maintain normal cell function. A disruption in one of the genes, called spns1, can induce degradation and premature “senescence” – or aging – while the other gene, called atp6v0ca, can jump in to suppress that degradation. Their experiments in zebrafish suggest that these combined genetic disruptions can counteract premature aging and extend developmental lifespan.
“We found that the dual defects did indeed counteract senescence during development and extended the animal’s survival and life span,” said TSRI Associate Professor Shuji Kishi...
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