prevention of aggressive prostate cancer tagged posts

Gene Signature predicts whether Localized Prostate Cancer is likely to Spread

META-16 is correlated with MYC and RAS pathway activation and enriched in prostate cancer metastasis.

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease. The new gene signature may also be useful for evaluating responses to treatment and for developing new therapies to prevent or treat advanced prostate cancer.

“If we could know in advance which patients will develop metastases, we could start treatments earlier and treat the cancer more aggressively,” says the study’s senior author, Cory Abate-Shen, PhD, chair of the Department of Molecular Pharmacology and Therapeutic...

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A More Complete Mediterranean Diet may Protect against Aggressive Prostate Cancer

Adjusted relative risk ratios (RRR) and 95% confidence intervals for the association between prostate cancer incidence and the scores of adherence to Western, Prudent, and Mediterranean dietary patterns in MCC-Spain study by tumor aggressiveness and extension. Credit: The Journal of Urology

Adjusted relative risk ratios (RRR) and 95% confidence intervals for the association between prostate cancer incidence and the scores of adherence to Western, Prudent, and Mediterranean dietary patterns in MCC-Spain study by tumor aggressiveness and extension. Credit: The Journal of Urology

New study in The Journal of Urology® finds that a high intake of fruits, vegetables, and whole grains might not be enough. Men who followed a Mediterranean diet, rich in fish, boiled potatoes, whole fruits, vegetables, legumes, and olive oil, and low consumption of juices had lower risk of aggressive prostate cancer (PC) than those who followed other dietary patterns like Prudent or Western diets.

Although PC is the most common type of cancer in men and can have a high mortality rate, evidence linking ...

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