probiotic tagged posts

Probiotic Delivers Anti-cancer Drug to the Gut

illustration of yeast Saccharomyces cerevisiae
Researchers at WashU Medicine shrink gastrointestinal tumors in mice using a yeast probiotic to deliver immunotherapy to the gut, offering a potentially novel strategy to target hard-to-reach gut cancers.

Oral immunotherapy shrinks gastrointestinal tumors in mouse study

Immunotherapy is a promising treatment that recruits the immune system to help fight cancer, but it has had limited success in gastrointestinal cancers. Now, researchers at Washington University School of Medicine in St. Louis have engineered a probiotic that delivers immunotherapy directly to the gut to shrink tumors in mice, offering a potentially promising oral drug for hard-to-reach cancers.

The probiotic cancer treatment, described Nov...

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Probiotic company finds Links between Youthful Gut Microbiota and Potential Centenarians

Probiotic company finds links between youthful gut microbiota and potential centenarians
Comparisons of microbial compositions between baseline and follow-up. (a) aPCoA of the Bray‒Curtis distance plot for baseline and follow-up after adjusting for hypertension, medication use, and alcohol and tea drinking. (b) α-Diversity differences between baseline and follow-up for stratified health statuses (HB, n = 21; HF, n = 15; LHB, n = 19; LHF, n = 27). (c) Composition of the gut microbiome at the phylum level between baseline and follow-up for stratified health statuses. (d) LEfSe between baseline and follow-up stratified by health status (two-sided Kruskal‒Wallis test between classes; P < 0.05, LDA > 2). Healthy baseline (HB, n = 21), healthy follow-up (HF, n = 15), less healthy baseline (LHB, n = 19) and less healthy follow-up (LHF, n = 27) samples were examined...
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Anxiety might be Alleviated by Regulating Gut Bacteria

Gut microbes illustration.
Credit: © nobeastsofierce / Adobe Stock

Review of studies suggests a potentially useful link between gut bacteria and mental disorders. People who experience anxiety symptoms might be helped by taking steps to regulate the microorganisms in their gut using probiotic and non-probiotic food and supplements, suggests a review of studies published today in the journal General Psychiatry.

Anxiety symptoms are common in people with mental diseases and a variety of physical disorders, especially in disorders that are related to stress. Previous studies have shown that as many as a third of people will be affected by anxiety symptoms during their lifetime.

Increasingly, research has indicated that gut microbiota – the trillions of microorganisms in the gut wh...

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Study Suggests a Minority Group of Gut Microbes may be Keystones of Health

Oregon study suggests some gut microbes may be keystones of health

A University of Oregon study finds abundance does not dictate the immune response to bacteria in the guts of zebrafish. This graphic depicts immune response (neutrophils, shown in green) to separate bacterial species, and the response when the two bacteria are placed into a germ-free fish gut at the same time. Credit: Courtesy of Annah S. Rolig

University of Oregon scientists have found strength in numbers doesn’t hold true for microbes in the intestines.The findings provide a path to study the function of each bacterial species in the gut and to eventually, perhaps, predict and prevent disease...

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