programmed death-ligand 1 (PD-L1) tagged posts

Novel Cancer Vaccine Strategy Blocks Death of Tumor-specific Cytotoxic T cells

Drs. Esteban Celis and Hussein Sultan in the Georgia Cancer Center at Augusta University laboratory. Credit: Phil Jones, Senior Photographer, Augusta University

Drs. Esteban Celis and Hussein Sultan in the Georgia Cancer Center at Augusta University laboratory. Credit: Phil Jones, Senior Photographer, Augusta University

New research published in Cancer Immunology Research by Drs. Esteban Celis and Hussein Sultan of the Georgia Cancer Center at Augusta University could serve as the stepping-stone in constructing vaccines with a greater likelihood of finding and attacking tumors in the human body. According to Celis and Sultan, the key in this vaccine strategy is increasing the amount of time a cytokine called interleukin 2 (IL2) stays in the body. IL2 is a molecule in the immune system responsible for regulating the activity of some white blood cells known as killer T cells.

“After administering peptide-based vaccines in mouse models of cancer, we ...

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