Genetic variant accelerates normal brain aging in older people by up to 12 years. Columbia University Medical Center (CUMC) researchers have discovered a common genetic variant that greatly impacts normal brain aging, starting at around age 65, and may modify the risk for neurodegenerative diseases. The findings could point toward a novel biomarker for the evaluation of anti-aging interventions and highlight potential new targets for the prevention or treatment of age-associated brain disorders such as Alzheimer’s disease.
“If you look at a group of seniors, some will look older than their peers and some will look younger,” sai...
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