Protect against Cancer tagged posts

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

The study, published in Nature Immunology, may lead to therapies that target the earliest stages of cancer. The findings bolster the idea that the inflammasome has a dual role: It promotes inflammation associated with poor outcomes in late cancer stages, but early on, it can help prevent cells from becoming cancerous in the first place.

“What was striking was that the in...

Goethe University researchers investigate oxidative stress in mice. Originally, oxygen radicals — reactive oxygen species, or ROS for short — were considered to be exclusively harmful in the body. They are produced, for example, by smoking or UV radiation. Because of their high reactivity, they can damage many important molecules in cells, including the hereditary molecule DNA. As a result, there is a risk of inflammatory reactions and the degeneration of affected cells into cancer cells.

Because of their damaging effect, however, ROS are also deliberately produced by the body, for example by immune or lung epithelial cells, which destroy invading ...