The cornea—the transparent protective outer layer of the eye critical to helping us see—produces a delicate and limited immune response to fight infections without damaging our vision, according to a new study from the Peter Doherty Institute for Infection and Immunity (Doherty Institute).
Published today in Cell Reports, the study has shown long-living memory T cells that patrol and fight viral infections are present in the cornea, upending current thought that T cells are not found in healthy corneas—expanding our understanding of the eye’s immune response to infections.
The team used a multiphoton microscope that provides live images of living, intact biological tissues to study cornea cells in mice infected with Herpes Simplex Virus.
Their images revealed long-livin...
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