proteosome inhibitor tagged posts

Aggressive form of Leukemia linked to Defective Ribosome, but can be treated

1. Professor Kim De Keersmaecker (KU Leuven, Belgium) is shown. Credit: KU Leuven - Rob Stevens. 2. In patients with multiple myeloma, the plasma cells in the bone marrow start proliferating malignantly.

1. Professor Kim De Keersmaecker (KU Leuven, Belgium) is shown.
Credit: KU Leuven – Rob Stevens. 2. In patients with multiple myeloma, the plasma cells in the bone marrow start proliferating malignantly.

20 – 40% of the patients with multiple myeloma have a defect in the ribosome, protein factory of the cell. These patients have a poorer prognosis than patients with intact ribosomes. At the same time, they respond better to a drug that already exists. These are the findings of a study by the Laboratory for Disease Mechanisms in Cancer at KU Leuven, Belgium.

Multiple myeloma (MM, also known as Kahler’s disease) is a blood cancer whereby the plasma cells in the bone marrow start proliferating malignantly. MM cannot be cured and is most common among older people...

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