PSA tagged posts

Researchers at the University of East Anglia have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods.

New research shows that the Prostate Screening EpiSwitch (PSE) blood test is 94 per cent accurate — beating the currently used prostate-specific antigen (PSA) blood test.

The research team say that the new test shows significant potential as an accurate and rapid cancer screening diagnostic.

The test was developed by Oxford Biodynamics in collaboration with UEA, Imperial College London and Imperial College NHS Trust.

Prof Dmitry Pshezhetskiy, from UEA’s Norwich Medical School, said: “Prostate cancer is the most common cancer in men and kills one man every 45 minutes in the UK.

“There is currently no single te...

A new type of test that uses complex sugars to detect prostate cancer earlier and with greater accuracy is being developed by researchers at the University of Birmingham. The test works by identifying sugars, known as glycans, in blood. These sugars are attached to protein molecules called PSA and are known to undergo distinct but subtle changes when cancer is present in the body.

Particular types of glycans are associated with different cancers – but until now, there has been no technology available to detect the glycans in an accurate, timely and sufficiently specific way.

Research led by a team in the University of Birmingham’s School of Chemical Engineering, has now developed a technique that can identify glycans associated with cancer with unprecedented accuracy...

IsoPSA(TM) Demonstration

IsoPSA assay can help in determining the need for prostate biopsy for patients. A team of researchers have demonstrated that a new blood test known as IsoPSA detects prostate cancer more precisely than current tests in two crucial measures – distinguishing cancer from benign conditions, and identifying patients with high-risk disease.

By identifying molecular changes in the prostate specific antigen (PSA) protein, the findings, published online last month by European Urology, suggest that once validated, use of IsoPSA may substantially reduce the need for biopsy, and may thus lower the likelihood of overdetection and overtreatment of nonlethal prostate cancer. The research team, led by Cleveland Clinic’s Eric Klein, M.D...