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Mechanism behind Reductions in Depression Symptoms from LSD and Mushrooms found

An international team of biotechnologists and neuroscientists has found the mechanism responsible for reducing depression symptoms in patients given two kinds of hallucinogenic compounds. In their mouse study, reported in the journal Nature Neuroscience, the group isolated binding receptors involved in the types of neural plasticity associated with improvements in depression symptoms. The editors at Nature Neuroscience have published a Research Briefing in the same journal issue outlining the work done by the team on this new effort.

For several years, mental health specialists have known that psychedelic drugs like magic mushrooms and LSD can reduce symptoms in patients with chronic depression. But until now, it was not known how such compounds function...

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