psoriasis tagged posts

Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body’s immune responses painlessly from the skin. The device detects inflammatory signals within minutes and collects specialized immune cells within hours without the need for blood draws or surgical biopsies.

Already, the patch is helping researchers and clinicians study immune responses in aging and skin autoimmunity, including vitiligo and psoriasis...

Researchers in China report that global incidence rates of psoriasis rose slightly from 1990 to 2021 and are projected to continue rising for both men and women through 2050.

Psoriasis is a chronic inflammatory skin disease that continues to impose a growing global burden. Understanding the rate of increase is critical for informing public health strategies, improving health care access, and supporting early diagnosis worldwide.

In the study, “Global Psoriasis Burden and Forecasts to 2050,” published as a Research Letter in JAMA Dermatology, researchers used a time-series forecasting analysis to project global psoriasis incidence through 2050 and to address age, sex, and regional differences in burden.

Analyses included age-standardized incide...

The skin’s top layer contains a diverse set of hundreds of lipid molecules called ceramides with varying chain lengths that play a vital role in its barrier function.

Ceramides are a type of lipid that are found in abundance in the top layer of the skin, called the stratum corneum...

An international research team has established a link between gut microbiota and chronic inflammatory diseases such as arthritis. The team led by Éric Boilard of Université Laval has discovered that a protein naturally present in the gut acts on the microbiota and causes the formation of molecules that exacerbate the symptoms of these diseases. The details of this finding are published today in the Journal of Clinical Investigation — Insight.

The protein in question, phospholipase A2-IIA, was discovered several years ago in the fluid that surrounds the joints of people with arthritis according to Dr. Boilard, a professor in the Faculty of Medicine at Université Laval and a researcher at CHU de Québec-Université Laval Research Centre...