receptor-binding domain tagged posts

After COVID vaccination, it usually takes weeks for our bodies to develop protective antibody responses. Imagine, however, a vaccine that speeds up the production of antibodies against SARS-CoV-2, the virus that spreads COVID-19.

A research team led by Rong Hai, an associate professor of microbiology and plant pathology at the University of California, Riverside, has developed such a vaccine by using preexisting immunity to a separate virus (the influenza virus) to help kickstart the process of making antibodies against SARS-CoV-2.

“Any delay in the immune response to SARS-CoV-2 means there is some time when people are left poorly protected against the virus,” Hai said...

The SARS-CoV-2 virus that causes COVID-19 has killed 6 million people worldwide since 2019.

Researchers now have discovered a monoclonal antibody that potentially acts as a potent universal coronavirus therapy against the COVID-19 virus and all its variants of concern, including delta and omicron. It also shows effectiveness against the deadly coronaviruses SARS, the Severe Acute Respiratory Syndrome that emerged in China in 2002, and MERS, the Middle East Respiratory Syndrome that appeared in Saudi Arabia in 2012. It even shows effectiveness against several common cold coronaviruses.

This universal activity results from the monoclonal antibody targeting a region of the viral spike protein that is highly conserved among beta-coronaviruses, yet i...